If you want to have a luxurious journey then rent a car from one of the major national car rental companies like National, Budget, Alamo, Hertz and Dollar. By road there is another option to choose and that is tour coach.
The coaches which are especially meant for traveling are offered by travel companies and through such coaches you can travel comfortably from Orlando to Busch gardens, the Kennedy Space Center, Miami and Everglades.
The services of Amtrak are limited to only certain destinations. However, train journey can also be considered as the best way for getting around Florida.